Welcome to our web site. Keeping current about health issues, fitness and life extnesion as we enter a new century means adding some new terms to your vocabulary. This decade brings with it an explosion of research and articles about 'Free Radicals' and 'Free Radical Pathology','Antioxidant Enzymes' and 'Live Enzyme Foods'. What you will find here at our site is a primer on this burgeoning area of science and nutrition in order to help you make sense of what you may read and learn in the months and years ahead.


ARTICLES

REPRINTS

ARTHRITIS HELP - Fighting Free Radicals by Michael Lemmon DVM

DOCTORS DIALOGUE - Is SOD the solution to ARTHRITIS, HEART DISEASE and AGING - by David A Steenblock MS. N.M.D., D.O.


ANTIOXIDANT ENZYMES AND YOUR HEALTH AND YOUR PETS HEALTH
While the nutritional balance needed to maintain healthy cells has remained much the same for thousands of years, man's foods have changed greatly. Food processing has lessened many vital elements available in commonly consumed foods. One class of elements eliminated almost entirely through food processing is enzymes. Vital elements that act as biological catalysts, particularly antioxidant enzymes, are crucial for the proper functioning of every cell in our body.

Antioxidant enzyme deficiencies have been documented in hundreds of published medical research studies. Although produced in our bodies, deficiencies can occur due to poor nutrition and the excess stresses of aging, pollution, surgery, radiation, overexertion, and illness.

ANTIOXIDANT ENZYMES PROMOTE THE NATURAL REMOVAL OF TOXIC WASTES


Clinical and double blind studies have demonstrated the complete safety and effectiveness of B&E Health products in providing the nutritional tools necessary to maintain proper antioxidant enzyme levels. Biotec live enzyme foods enhance and develop the natural health and beauty inherent in everyone. When this natural radiance is nurtured and allowed to blossom, the result is a happy blend of relaxation, vitality and overall well-being. Thanks to advanced food genetics, you now can have the energy to do effortlessly the things you've always dreamed of.

Our body cells constantly produce enzymes to protect us from cell damaging substances called free radicals. Excess free radicals come from environmental pollutants, radiation, illness, excess sun, overexertion, poor nutrition, aging and even emotional stress. All of these factors create a condition in which our body's production of enzymes is less than our needs. The result of this enzyme deficiency is cellular damage often seen as inflammation and pain.

This cellular damage can be prevented if the proper enzyme complexes are present in amounts large enough to overcome the amount of free radicals. Stresses in today's environment, lifestyles, poor nutrition and aging itself challenge our body's ability to meet our enzyme needs. In providing the necessary enzyme complexes, B&E Health products are a major nutritional breakthrough in preventive health care.

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FREE RADICALS


WHAT ARE FREE RADICALS AND HOW DO THEY AFFECT MY BODY AND MY PETS BODY?
A free radical is any atom or molecule with an unpaired electron. This is a very unstable state. A free radical will react with other molecules in an attempt to "steal" an electron for the unpaired one. But the molecule that has had an electron stolen from has now become the free radical and will attempt the same with other molecules. This can start chain reactions which can cause significant damage throughout our bodies.

For protection, our cells have antioxidant mechanisms which can scavenge these free radicals. It's when these antioxidant systems become overwhelmed that we run into problems (ie, aging, disease). Anyway, I hope this serves as a brief introduction.


What are free radicals?Where do free radicals come from?

How do free radicals hurt the body? | How does the body defend itself?

What increases antioxidant levels? | What is the best way to get live foods?

WHAT ARE FREE RADICALS?
Like all matter, our bodies are composed entirely of tiny particles called molecules. Each molecule is made up of atoms, and each atom is made up of a center or nucleus and electrons which spin in orbits around it.

Ordinarily, the electrons occur in balanced pairs. This keeps the atom and molecule stable. Sometimes a molecule loses one of its electrons or gains and extra one. This causes the molecule to become unbalanced and highly reactive. Such a molecule is called a 'Free Radical'.

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WHERE DO FREE RADICALS COME FROM?

Some 'Free Radicals' occur as normal by-products of a healthy body's metabolic processes. Overproduction of "Free Radicals' occurs when the body is subjected to 'Stress' in any of its many forms:

Types of Stress

Chemical Emotional Physical Infectious

Common Stress Sources

Aging Environmental Pollutants Trauma
Disease Pace & Pressure of Modern Life

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HOW DO FREE RADICALS HURT THE BODY?
Having unpaired electrons is not an energetically favorable or stable state for a molecule. A 'Free Radical' will naturally try to return to a state of stability by taking an electron from some other molecule and restoring its own balance. It is this little act of thievery that causes the damage. The stolen electron may be from a molecule in a normal healthy cell. This process of 'Cell Damage' continues to multiply if not checked. The end result is that the healthy cells are damaged and the body's proper functioning is impaired.

Unfortunately today, the increased stresses of modern life combined with age and the nutritional inadequacies of a contemporary diet result in an excess of free radical activity in the body and a deficiency in the available supply of antioxidants to remove them. This negative state is known as 'Free Radical Pathology'.

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HOW DOES THE BODY DEFEND ITSELF?
Nature equips the body to produce special enzymes called 'Antioxidants' which catalyze the removal of the 'Free Radicals' before they can cause cellular damage. Under normal conditions these naturally occurring 'Antioxidant Enzymes' can handle the 'Free Radicals' produced by the body's own metabolic processes.

In addition, nature allows the body to acquire additional supplies of these antioxidant enzymes from certain raw foods.

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HOW CAN I MAXIMIZE MY BODY'S DEFENSES?
The first line of defense is to eat certain whole, natural, 'Live Foods' which are rich in enzymes themselves, and which appear to stimulate the body's own production of antioxidants.

However, it's not always convenient to eat fresh whole foods, and unless you grow your own, the nutritional value of those you do eat may be questionable. Modern agricultural practices have greatly depleted the nutritional value of the foods we eat, even raw fresh foods.

Today, vegetables are bred for longer shelf life, convenience in shipping and high yield, not necessarily for high nutrition. Important trace elements and other co-factors which make the enzymes usable to the body often are missing. The nutritional content is even further reduced by the heat of cooking which destroys the live enzymes.

The 'Live Enzyme' foods that provide the best sources of antioxidant enzymes include; Raw vegetables, wheat grass, barley grass, sprouts and blue-green algae.

Prescription for Nutritional Healing states, "Of all raw foods, sprouts are the richest source of natural food enzymes.

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WHAT IS THE BEST WAY TO GET LIVE FOODS?
Fortunately, recent years have brought some very beneficial research and new technological developments in plant management.

Biotec Foods has developed and grows enhanced strains of blended sprouts which are enzyme-rich and which have been shown to increase the endogenous production of antioxidant enzymes in the human body. These sprout blends are dehydrated at low temperatures to prevent damage to the live enzymes and then highly concentrated and compressed into a convenient tablet form.

These 'Live Enzyme' food supplements from B&E Health are available under several product names. Each product formula is specially blended with IsoSproutplex™ to provide the required antioxidant enzyme protection based on individuals personal activity and needs.

Thanks to Modern Technology, you don't need to have your own organic farm to enjoy the benefits of eating 'Live Enzyme Foods'. The nutrition you need is as available in a convenient 'concentrated caplet or tablet from B&E Health.

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STRESS & IMMUNITY

STRESS AND IMMUNITY
Stress is a relatively new notion that everybody talks about, yet few understand. The dictionary defines stress as "pressure, force, strain; a state of physical or mental tension inducing it, or affecting something.' This definition, while obviously correct, is not very helpful in understanding the concept of stress. On the other hand, it is important to comprehend the notion, because all of us are continuously exposed to stress. Stress occurs in many forms. The four major categories which concern us are:

Types of Stress

Chemical Stress Emotional Stress Physical Trauma Infectious

These all can lead to oxidative stress

Each of these stress forms can originate from multiple sources. Most of these have appeared as primary threats in our environment as recently as this century. For example, chemical stress can come from pesticides, insecticides, polluted air and water, heavy metals such as mercury or lead, asbestos and worst of all radioactive waste. Even jet travel, a welcome commonplace today but unheard of a mere half century ago, exposes passengers to an unhealthy high level of ozone and random cosmic radiation's. In the light of such widespread physiological insult, it is a true miracle that any if us manage to stay healthy at all.

One of the primary reasons why stress is so important to understand, is because it is intricately linked to the functioning of our immune systems. How many of us have gotten a cold when our defenses were impaired by excessive stress? This is another angle from which to view to view the recent rash of immune disorders unleashed in our culture. Could these problems be partly caused by an overwhelmed immune system? It should be obvious that this is quite possible, and the more we consider the high levels of stress that most of us are exposed to daily, the more relevant the idea become. In other words, understanding and compensating for the stress in our lives will help our immune systems and enhance our ability to stay well.

This is not to imply that all stress is harmful. Exercise, for example, is a form of stress on the body which is quite healthy. Yet if we over-exert ourselves during exercise, we can damage the body and create problems. As we have already mentioned, many unavoidable stress factors, such as pollution, and others that cause damage to the body, stem from today's world of technological progress. In many cases the physical result brought on by several different forms of stress is the same. The unnecessary, but avoidable results are cellular damage caused by over-reactive molecules called "Free Radicals."

Due to their over-reactive nature, free radicals can be extremely toxic and are a direct consequence of the primary stress factors that adversely affect the immune system and threaten our health. However, this is not to imply that free radicals are always harmful or dangerous. Minute amounts of free radicals are essential for many important functions of the immune system and other vital cellular activities. For example, the immune system will actually generate free radicals to use in the process of removing a virus or bacteria. Only when high concentrations of free radicals are present, or when the levels of free radicals overwhelm the body's ability to remove them, does the threat to our health occur.

Maintaining the balance between free radical activity and antioxidant enzyme supply is one of the important functions of the body (Fig. 1)

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ANTIOXIDANT ENZYMES


THE MAIN ANTIOXIDANT ENZYMES

Even though the production of antioxidant enzymes in the body is a complex process that is not yet totally understood, there are several processes that we are aware of and which seem to constitute a large part of the finished system.

The antioxidant enzyme defense system consists of hundreds of different substances and mechanisms. This is why only an adequate combination of whole foods, such as sprouted food concentrates, will contain all of the known and unknown nutritional factors that the body requires to enhance its antioxidant enzyme supply.



SUPEROXIDE DISMUTASE & CATALASE
We are a species that cannot live without breathing. As a result of this circumstance, oxygen has turned into a synonym of life. A fact much less known is that not all oxygen atoms are life supporting. Some are actually quite destructive for our cells. These unhealthy oxygen atoms are unbalanced and constitute the most common "Free Radical" known. The "Oxygen Free Radical" is characterized by having and unpaired electron in its molecular structure. Called " Superoxide", it is quite capable of causing cell damage.

The first line of defense that the body has against superoxide free radicals is the enzyme known as "Superoxide Dismutase" or (SOD), which is considered the most effective antioxidant. The importance of SOD is so paramount for the protection of our cells, that it represents a substantial proportion of the proteins manufactured by the body. In brief, SOD keeps oxygen under control.

In the process of removing superoxide free radicals, SOD rarely operates alone. It requires the enzyme called " Catalase" or (CAT) to remove hydrogen peroxide molecules which are by-products of the reactions created by SOD. Similar to SOD, CAT is abundant in the body. Integrated in all red blood cells, CAT removes hydrogen peroxide from our tissues, preventing both cell damage and , more importantly, the formation of other more toxic free radicals. In nature, and in the body, SOD and CAT always co-exist.

The natural interaction - synergy - between these two antioxidant enzymes constitute the most effective system of free radical control in our bodies.

Superoxide free radicals initiate the breakdown of "Synovial Fluid" ( the lubricating element in the joints of our bodies) causing friction and , eventually, inflammation. For this reason, the attention of clinical SOD research has been focused primarily on inflammatory processes triggered by superoxide free radicals such as arthritis, bursitis and gout.

Deficiency in SOD/CAT is the most notorious nutritional factor in most 'inflammatory' processes. Recent applications of SOD/CAT enhancing foods have also proven to be extremely useful as a (pre- & post) operative supplement which stimulates recovery and reduces convalescence periods remarkably.

Considering the powerful link between free radicals and many of today's health problems, supplements that enhance SOD/CAT activity in the body offer tremendous potential in the field of preventative nutrition.


GLUTATHIONE PEROXIDASE
Glutathione Peroxidase is another of the body's major protectors against free radicals. This antioxidant enzyme consists of the amino acid Glutathione and the trace mineral 'Selenium'. These two nutrients team up to combat a specific class of free radicals called peroxides. the main biological function of selenium in mammals is a component of the Glutathione Peroxidase enzyme. Many of the attributes of selenium and Glutathione are actually attributes of Glutathione Peroxidase.

Cell membranes consist primarily of lipids (fats). These lipid membranes are very susceptible to damage by free radicals, especially peroxide radicals. This is why rancid fats (lipid peroxides) have proven to be highly toxic. Glutathione Peroxidase prevents destruction of cell membranes by removing several classes of these lipid peroxides.

The main symptoms of excess peroxide free radicals include heart disease, liver disease, premature aging and skin disease such as skin cancer, eczema, wrinkling, age spots, dermatitis and psoriasis. Peroxide free radicals mediate much damage to the body by impairing liver functions. Consisting of nearly 50% fatty tissue, the liver is very susceptible to lipid per oxidative damage.

Although used primarily for skin related problems, many environmentally sensitive and chemically poisoned people report that Glutathione Peroxidase helps them control their allergies and build resistance to the effects of pollution. Generally speaking, all of the antioxidant enzymes are important where pollution is a concern due to their ability to remove free radicals generated by toxic substances. The list of protective effects of Glutathione Peroxidase is growing and is in no way limited to any single symptom such as age spots. The effects of excess per oxidation in our cells is diverse and dangerous and must be limited to maintain cellular health.


METHIONINE REDUCTASE
Methionine Reductase is a unique enzyme that has demonstrated an ability to remove an extremely toxic free radical called the "Hydroxyl Radical". The hydroxyl radical is commonly formed through reactions involving heavy metals and other less toxic free radicals, such as mercury reacting with hydrogen peroxide. The hydroxyl radical has the ability to damage any type of organic tissue and is considered to be the most dangerous free radical. Hydroxyl radicals are also the main toxins generated by exposure to excessive radiation. With their ability to damage any type of tissue, symptoms directly related to hydroxyl radical induced tissue damage are difficult to identify.

One effective detoxifying application for Methionine Reductase is in the removal of free radical toxins generated by the mercury found in dental fillings. Another interesting application of Methionine Reductase is for the modern day athlete. It seems that hydroxyl radicals are also formed during exercise. This is especially true if we are exercising in oxygen starved closed rooms or in a auto exhaust filled polluted environments. It is amazing to see joggers running along the road during rush hour traffic. Quite possibly, they are doing more harm than good!

Most avid exercisers are always aware of the need to obtain extra nutrition to fuel their activities. What many miss, is the importance of cleaning out the extra metabolic wastes that are a direct result of this exercise. Hydroxyl radicals can be created when we burn fat molecules to produce energy as in strenuous exercise or dieting. This is due to the lack of evacuation of chemicals and toxins stored in the fatty tissue which are released when these tissues are used for fuel. These toxins, when not properly evacuated, generate the formation of hydroxyl radicals.

People supplementing their diets with "Methionine Reductase" have reported greater resistance to the ill effects of pollution as well as greater endurance, stamina, flexibility and the ability to recover from extensive exercise. Although it is generally important to exercise, our modern civilized environments force us to compensate for free radical by-products if we wish to gain health or longevity form our workout programs.

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ARTHRITIS HELP

Fighting Free Radicals

by Michael Lemmon, DVM

     What are free radicals? They sound dangerous - and they are. You may have read about them recently in connection with the aging process and with degenerative diseases. How are they formed? What kind of damage do they do? Most importantly, how does the body protect itself against them?

Arthritis

     One of the contributing causes of arthritis is the excess accumulation of free radicals in the joint capsule - the fluid-filled sac surrounding every joint in the body.

     This fluid, or "joint oil" is kept healthy with the help of enzymes produced by the body. The enzymes act like soap - they clean away the free radicals - keeping the joint properly lubricated and allowing free movement. Otherwise, the free radicals would slowly eat away the lining of the joint capsule, causing pain and swelling.

     Those with arthritic animals know the stiff, painful legacy of the disease, as joints get seemingly "frozen" into position.

     What can be done about this? First, it helps to know where the free radicals come from.

     Free radicals are formed during normal cellular metabolism, when cells take in nutrients, assimilate and utilize the nutrients, and then excrete the waste products.

     Some of these waste products are free radicals. Wherever you find poor quality foods being eaten, you will also find an excess of free radicals.

Food Link

     Rancid fats and moldy grains are two leading sources of free radical production in both animals and humans. Where do they come from?

     Fat is an essential ingredient in any diet. Rancidity is caused by oxidation of fats during processing or storage of foods. Mold often occurs from storage conditions. Often chemicals which are sprayed or added to foods to help control other problems increase free radical production in foods. Chemicals and pollutants in our air, water, and food supply also significantly   increase free radical production in the body.

     Free radicals, if they are not neutralized by antioxidants, will cause damage to the body's tissue systems.

     There is, however, protection. Many cases of arthritis will respond effectively and quickly to a selected diet of fresh foods avoiding rancid fats, moldy grains and chemicals that are present in processed, commercial foods. Since most owners must rely on the convenience of commercial foods, it becomes doubly important to supplement their animal's diets with antioxidants. 

SOD and Catalase

     A highly effective antioxidant is the enzyme combination of superoxide dismutase (SOD) and catalase (CAT).

     These two enzymes are produced in the cells of both animals and humans. We are each born with an enzyme "bank". Babies have twice as much SOD - catalase as adults. These SOD - catalase enzymes are the most free radical destroyers. They also help remove other poisons and toxins.

     The body's ability to to produce SOD - catalase decreases with age. There is good evidence that over time, the excessive use of the body's enzyme systems also decreases this enzyme production. Sparing the body's enzyme "bank", or reserve, by consuming raw foods that are rich in enzymes helps solve this free radical problem.

     Another solution is to take SOD - catalase enzyme supplements. The most effective are derived from specially grown wheat sprouts. The wheat sprout tablet form of SOD - catalase is the most beneficial source of antioxidant protection because they are whole foods and contain both ' live' enzymes and all the nutritional co-factors to complete utilization.

     These supplements have proven to be very helpful for arthritis and other geriatric degenerative in my practice as well as in the practice of other veterinarians throughout the country. SOD - catalase supplements are harmless and do not have any negative side-effects.

     The amount given depends on the size of the animal and also on the severity of the condition. Sometimes amounts of six or more tablets are given daily to more reduce the buildup of free radicals and other toxins in the body. This reduces the pain and inflammation of the condition, allowing the veterinarian to prescribe lower doses as needed. Relief of free radical toxins also promoted vitality and speeds healing when an animal is injured or undergoes surgery.

     Rather than treating arthritis and other degenerative problems in animals with heavy doses of steroids and other drugs - which have harmful side effects - we can instead rely on the use of simple, effective whole food antioxidants that work in harmony with the body assisting in it's daily routine, helping to alleviate pain, discomfort, and disease.

About The Author

     Michael Lemmon, DVM is a holistic veterinarian based in Renton, WA. At his Highlands Veterinary he practices both complimentary (holistic) medicine and conventional (allopathic) medicine. He has appeared on local TV and radio shows. He serves on the boards of the American Holistic Veterinary Medical Association, and Resort of the Mountains, a rustic retreat center specializing in health care, cleansing and rejuvenation.

Be sure to ask about Biovet Internationals' Advanced Antioxidant Enzyme supplements for animals.

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DOCTOR'S  DIALOGUE

Reprinted with the permission of LET'S LIVE Magazine

  Is SOD The Solution To Arthritis, Heart Disease And Aging?

By David A. Steenblock, M.S. , N.M.D., D.O.

Sometimes we need a natural, safe and effective treatment if we are sick. SOD (superoxide dismutase) is a natural, safe enzyme that has helped treat a variety of health problems. Arthritis and other auto immune conditions such as lupus, respond well to this agent. These inflammatory diseases are due in great degree to the reaction of white blood cells on tissues. White blood cells generate harmful free radicals such as superoxide anion (an oxygen molecule that has acquired an extra electron). Free radicals are like sparks and smoke from a bonfire that isn't getting enough air. Sod "soaks up" these sparks and smoke, turning them into harmless substances.

     SOD has been shown to be a unique, anti-inflammatory drug by virtue of a combination of the following characteristics:  It is effective; it can be taken with other anti-inflammatory; it's effects are long lasting; treatment can be adjusted to the location of the disease (this applies only to the inject able form); it is nontoxic and causes no adverse side effects; it generally doesn't cause allergic reactions; and it doesn't interact with other drugs to cause side effects.

     In addition to it's effectiveness in the treatment of osteoarthritis, rheumatoid arthritis, lupus and other autoimmune disorders, SOD appears to be beneficial in treating other age related disorders.

     Recent research indicates that when tissue undergoes a period of lack of oxygen (hypoxia), followed by the reestablishment of the oxygen supply, free radicals form in the blood vessel wall's inner lining. These free radicals cause extensive damage to the vessel wall, opening holes through which water, calcium and other substances penetrate the tissues. This accumulation of fluid and calcium causes further damage and is what injures and/or kills the tissues when they temporarily lose their oxygen supply.

     Currently, surgeons are considering using SOD during the postoperative phase of open-heart-surgery, since experimental work has demonstrated that this enzyme protects the tissues from surgical trauma. In addition, transplant surgeons are beginning to administer SOD in order to keep organs alive for long periods of time once they're taken out of the body.

     The inner linings of blood vessels manufacture SOD, which helps prevent the white blood cells known as PMNs (polymorphs) and monocytes from sticking to the blood vessel wall. When body tissue is without oxygen for extended periods of time, the amount of SOD present in blood vessel linings may have so many free radicals generated that the enzymes are not able to remove them at all. This short supply of SOD causes damage or death of the tissue from the excessive amounts of free radicals. Some people naturally maintain higher levels of SOD than others. The level of SOD and other antioxidants in our blood vessels is controlled, in part, by our genes. How our genetic mechanisms function in the production these antioxidant enzymes may partly explain why some of us live long, healthy lives while others die prematurely.

     In addition to the health of our blood vessels, the overall health of our tissues may depend on the amount of antioxidants in them. In recent studies, high levels of SOD in relation to metabolic rates were shown to correlate directly to longevity. These results suggest that the SOD-to-superoxide-anion ratio in our tissues relates to how long we live (the more SOD and fewer free radicals your tissues produce, the longer you will live).

     SOD may play a role in treating Alzheimer's disease and senile dementia. Recent studies indicate that the areas in the brain affected by the diseases are the same areas that suffer free-radical damage from hypoxia-reperfusion injury. The identification and treatment of people at risk for hypoxia-reperfusion injury is difficult because those who are affected tell themselves that becoming forgetful is "normal", when in fact it should never be considered normal. I have used chelation therapy, along with SOD and other antioxidants, in many cases of early dementia and have seen excellent results. A paper describing my treatment methods is available by sending a stamped, self-addressed, large envelope to "Dementia" at the address at the end of this article.

     Alcohol has been shown to produce the superoxide anion, and alcohol produces the scarring of the liver leading to the condition known as cirrhosis of the liver.  SOD should be taken by anyone who drinks to help development of scar tissue. The same holds for those of us with high cholesterol and a family history of heart disease. We need to do everything we can to prevent the development of atherosclerosis.

     In the last year, health food companies have developed whole-food antioxidant enzyme complexes containing high quantities of SOD, aling with catalase and glutathione reductase. The new products are unique in that they are vegetable concentrates in in an enteric coating, which keeps them from being destroyed by the stomach's acid. In the past, SOD was available in the form of pills containing very little SOD. The new pills each contain more than 1.5 million units. Consult your nutritionally oriented physician to determine the proper dosage for you.

     Dr Steenblock, a member of our Medical Advisory Board, is president of the Anti-Aging Research Institute of America.  

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